Figure 5

Lung Mechanics. Mechanics parameters following nebulized saline and increasing concentrations of methacholine (peak response as percent of baseline). Groups; naïve mice (N) (n = 7) and OVA mice treated with vehicle (V) (n = 6), salmeterol (S) (n = 7), fluticasone (F) (n = 8), salmeterol and fluticasone (FS) (n = 8). R = R _N = Newtonian resistance, G = tissue damping, H = tissue elastance. Results expressed as mean ± SE Panel with R: NS no significant differences between the groups. Panel with G: * p < 0.05 for S compared to V, N, F, or FS. Panel with H: * p < 0.05 for S compared to V (p is also < 0.05 for S compared to N, F, or FS). † p < 0.05 for S or V compared to N, F, or FS. All comparisons in this figure are by a two way ANOVA followed by Tukey pairwise comparisons.