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Figure 2 | Respiratory Research

Figure 2

From: Effects of PPARγ ligands on TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells

Figure 2

Regulation of basal E-cadherin and N-cadherin expression by PPARγ ligands. (A) Effect of TGF-β1 or PPARγ ligands on expression of epithelial marker E-cad (n = 4). (B) Effect of TGF-β1 or PPARγ ligands on expression of mesenchymal marker N-cad (n = 4). Cell lysates were prepared from A549 cells pre-incubated with vehicle, TGF-β1 (2.5 ng/ml), or RGZ or CGZ at the concentrations indicated for 72 hr. Densitometric analysis values for band intensities from each Western blot were normalised to β-actin and expressed as a percentage of basal levels. Each point represents mean ± s.e.m.

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