Figure 3

Lung histopathology at 21 days in male AKR mice treated with RSV and/or V ₂ O ₅ . (A) Representative airway pathology in mice exposed to V₂O₅ with or without RSV pre- or post-exposure. Lung sections were stained with Masson's trichrome to show collagen (blue staining). (B) Inflammation scores were determined in a blinded manner as described in Methods. Data were analyzed by One-way ANOVA followed by Tukey's test. **P < 0.01 or ***P < 0.001 compared to V₂O₅. (C) Lung collagen was measured by Sircol™ assay as described in Methods. Data were analyzed by One-way ANOVA followed by Tukey's test. **P < 0.01 compared to Control.