| |
Grade 1
|
Grade 2
|
Grade 3
|
composite bronchiolization score
|
|---|
|
Wild-type (C3H) (n = 8)
|
2.9 ± 1.0
|
2.0 ± 0.8
|
3.0 ± 1.3
|
13.4 ± 4.0
|
|
Acatalasemic (n = 6)
|
6.7 ± 2.0
|
2.0 ± 0.7
|
3.0 ± 1.1
|
28.3 ± 5.0*
|
- *: p < 0.05 vs. Wild-type mice (C3H/AnLCsaCsa) (Mean ± SE)
- Grade 1: Single alveolus lined by cuboidal epithelial cells or a single isolated acinar structure consisting of cuboidal epithelial cells adjacent to a terminal bronchiole
- Grade 2: 2 to 4 clustered tubular structures consisting of single-layered cuboidal epithelial cells adjacent to a terminal bronchiole
- Grade 3: More than 4 clustered tubular structures single-layered or stratified cuboidal epithelial cells
