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Table 2 Summary of the results of the ten different classification tasks.

From: Identification of lung cancer with high sensitivity and specificity by blood testing

Classification task

Accuracy %

Sensitivity

%

Specificity

%

lung cancer vs controls

97.6

(CI: 97.3-97.9)

97.9

(CI: 96.6-97.8)

97.0

(CI:97.6-98.3)

lung cancer stage IA/IB vs controls

92.9

(CI: 92.4-93.4)

75.9

(CI: 73.7-78.2)

97.6

(CI: 97.3-97.8)

lung cancer stage II, III, IV vs controls

97.6

(CI: 97.1-98.0)

99.9

(CI: 87.2-91.0)

89.1

(CI: 99.7-100.0)

lung cancer stage IA/IB vs lung cancer stage II, III, IV

66.5

(CI: 63.8-69.1)

65.7

CI: 62.2-69.2)

67.3

(CI: 64.6-70.0)

NSCLC vs controls

94.6

(CI: 93.9-95.2)

97.8

(CI: 97.5-98.2)

85.7

(CI: 83.8-87.5)

SCLC vs controls

95.7

(CI: 95.2-96.0)

99.3

(CI: 99.0-99.6)

79.4

(CI: 77.5-81.4)

NSCLC vs SCLC

67.3

(CI: 65.4-69.3)

76.7

(CI: 74.4-79.0)

52.2

(CI: 50.0-54.4)

lung cancer vs NTLP

88.5

(CI: 88.0-89.3)

99.8

(CI: 99.5-100.0)

42.4

(CI: 40.2-44.6)

lung cancer vs non-cancer

92.2

(CI: 91.6-92.9)

96.7

(CI: 95.5-97.9)

88.2

(CI: 87.5-88.8)

lung cancer vs COPD/emphysema

78.8

(CI: 78.0-79.7)

92.6

(CI: 91.6-93.5)

40.9

(CI: 38.8-43.0)

  1. Abbreviations: NSCLC = non-small cell lung cancer, SCLC = small cell lung cancer, NTLP = non-tumor lung pathology, controls = patients without any lung disease, non-cancer = controls and NTLP, CI = 95% Confidence Intervals