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Table 1 Characteristics of healthy controls and CF patients, divided in subgroups according to P. aeruginosa infection status

From: Elevated expression of both mRNA and protein levels of IL-17A in sputum of stable Cystic Fibrosis patients

 

CF never/free/intermittent P. aeruginosa

CF chronic P. aeruginosa

control subjects

Nr. of subjects

17

21

11

Age (mean ± SD) in years

26.6 ± 8.0

25.1 ± 4.3

27.5 ± 10.9

Gender (F/M)

11/6

9/12

10/1

BMI (mean ± SD) in kg/m2

21.6 ± 3.0

20.2 ± 2.5

NA

Genotype (# of pts dF508del homozygous)

2

16*

NA

Exocrine pancreas insufficiency (%)

64.7

100**

NA

Current FEV1 (% predicted) (mean ± SD)

72.8 ± 17

61.9 ± 17.4

Normal values

Mean FEV1 previous year

(% predicted)

(mean ± SD)

73.8 ± 16.6

65.1 ± 16.3

NA

  1. SD: standard deviation, F: female, M: male, NA: not available, pts: patients.
  2. *: p < 0.0001 (Chi-square test), **: p = 0.003 (Chi-square test).