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Table 1 Studies connecting spirometric values or incidence of respiratory infections with Vitamin D.

From: A systematic review of the role of vitamin insufficiencies and supplementation in COPD

Vitamin D-Ref

No of participants

FFQ or plasma levels

Results

[33]

18.883

Plasma levels

Lower 25(OH)D levels were independently associated with recent URTI (odds ratio [OR], 1.36-1,24). The association between 25(OH)D level and URTI was stronger in patients with chronic obstructive pulmonary disease odds ratio; 2.26.

[35]

800

Plasma levels

Subjects with serum 25(OH)D concentrations < 40 nmol/L (n = 24) had significantly (P = 0.004) more days of absence from duty due to respiratory infection (median: 4; quartile 1-quartile 3: 2-6) than did control subjects (2; 0-4; n = 628; incidence rate ratio 1.63; 95% CI: 1.15, 2.24).

[72]

14.091

Plasma levels

The mean difference between the highest and the lowest quintile of 25-hydrocyvitamin D serum concentration was 126 mL (SE:22 mL) in FEV 1, and 172 mL (SE:22 mL) for FVC.