Table 3 Treatment comparisons for 10 min post challenge mean TNSS and mean nasal PIF over the last three days of the allergen challenge series.
Variable | Treatment | Mean differencea | 95% CI | P-value |
|---|---|---|---|---|
TNSS | AZD3778 vs. placebo | -1.56 | -2.03, -1.09 | <0.001 |
Loratadine vs. placebo | -1.87 | -2.34, -1.4 | <0.001 | |
AZD3778 vs. loratadine | 0.312 | -0.149, 0.773 | 0.181 | |
Nasal PIF | AZD3778 vs. placebo | 16.8 | 5.73, 27.9 | 0.004 |
Loratadine vs. placebo | 8.67 | -2.43, 19.8 | 0.124 | |
AZD3778 vs. loratadine | 8.14 | -2.83, 19.1 | 0.143 |