Table 2 Period means and ranges for pre- and 10 min post-allergen challenge mean TNSS and mean nasal PIF over the last three days of the allergen challenge series.
Pre challenge | 10 min post challenge | |||||
|---|---|---|---|---|---|---|
Variable | Treatment | n | Mean | Range | Mean | Range |
TNSS | AZD3778 | 35 | 1.25 | 0, 3 | 4.11 | 0.7, 7.7 |
Loratadine | 35 | 1.64 | 0, 8 | 3.85 | 1, 8 | |
Placebo | 34 | 1.56 | 0, 5.5 | 5.57 | 1.7, 9 | |
Nasal PIF | AZD3778 | 35 | 179 | 76.7, 247 | 125 | 50, 200 |
Loratadine | 35 | 165 | 50, 243 | 114 | 30, 210 | |
Placebo | 34 | 177 | 100, 257 | 108 | 57, 177 | |