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Figure 5 | Respiratory Research

Figure 5

From: Reverse mode Na+/Ca2+ exchange mediated by STIM1 contributes to Ca2+ influx in airway smooth muscle following agonist stimulation

Figure 5

Effect of 10 μM CPA and 20 μM SK&F 96365 on HA induced NCX1 currents in HBSMCs. (A) Time course of NCX1 subtracted outwardly rectifying current density (at +80 mV) ± CPA or SK&F 96365. Control (squares, n = 11), CPA (diamonds, n = 12) and SK&F 96365 (triangles, n = 11). B) Bar chart illustrating peak current density of NCX1 outwardly rectifying current in control (n = 11) compared with cells treated with CPA (n = 12) or SK&F 96365 (n = 11) (mean data ± SEM, *p < 0.05). C) Representative traces of I-V relationships of NCX1 currents ± CPA or SK&F 96365.

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