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Figure 5 | Respiratory Research

Figure 5

From: Variability in the precursor proteins of collagen I and III in different stages of COPD

Figure 5

Precursor protein of collagen I in the large airways of non-smokers, smokers and the patients with COPD. Thickness of subepithelial layer expressing precursor protein of collagen I displayed an increase of this protein in smokers and in patients with stage I-II COPD compared to non-smokers. Its thickness was highly diminished in the patients with very severe COPD. The difference between stage I-II and stage IV COPD was statistically significant.

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