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Figure 3 | Respiratory Research

Figure 3

From: Variability in the precursor proteins of collagen I and III in different stages of COPD

Figure 3

Immunohistochemical staining for precursor protein of collagen III in bronchus of a non-smoker (A), a smoker (B), a patient with mild (stage I) COPD (C) and a patient with very severe (stage IV) COPD (D) showing that in large airways, the subepithelial layer that was positive for precursor protein of collagen III was thicker in smokers and in stage I-II COPD compared to non-smokers and patients with stage IV COPD.

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