Figure 10
From: Variability in the precursor proteins of collagen I and III in different stages of COPD
Spindle-shaped, alpha-smooth muscle actin positive fibroblastic cells were found to co-localise with collagen III propeptides in serial sections of central bronchi. Almost no expression of collagen I propeptides was seen (A-D), but there was variable expression of collagen III propeptide (E-H) and co-localization of spindle-shaped alpha-smooth muscle actin positive fibroblastic cells (I-L, arrows), with immunohistochemistry for vimentin (M-P, P with negative anti-rabbit-control).