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Table 3 CD4+ and CD8+ T cell response to mycobacterial virulence factors

From: Multiple mycobacterial antigens are targets of the adaptive immune response in pulmonary sarcoidosis

 

Sarcoidosis

PPD-

NTM

P-value

Total Subjects

31

14

9

 

CD4+ Response to any mycobacterial antigen

22

2

5

0.0008*

CD4+ Response to multiple mycobacterial antigens

16

2

4

0.02*

CD8+ Response to any mycobacterial antigen

18

2

3

0.009*

CD8+ Response to multiple mycobacterial antigen

12

2

3

0.12*

  1. *Comparison of Sarcoidosis to PPD- subjects by two-tailed, Fisher's exact test. CD4+ or CD8+ response was defined as positive when the frequency of recognition was at least twice background fluorescence and greater than 0.5%.
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Respiratory Research

ISSN: 1465-993X

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