Figure 4
From: Multiple mycobacterial antigens are targets of the adaptive immune response in pulmonary sarcoidosis
Sarcoidosis CD8+ BAL T cells produce IFN-γ in response to multiple mycobacterial antigens. Percent CD8+ cells that produce IFN-γ after stimulation with neoantigen (KLH), ESAT-6, katG, Ag85A, sodA, and HSP. Differences in the CD8+ immune response across diagnosis groups were noted using the Wilcoxon rank sum test. Medians are depicted by lines. Stimulation of BAL cells with SEB resulted in a positive IFN-γ response for sarcoidosis subjects and disease controls. The p values listed are for the comparison between sarcoidosis and PPD-. No significant difference was seen between sarcoidosis and NTM group.