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Figure 1 | Respiratory Research

Figure 1

From: Oral tolerance inhibits pulmonary eosinophilia in a cockroach allergen induced model of asthma: a randomized laboratory study

Figure 1

Oral tolerance improves pulmonary respiratory parameters. Penh and resistance (A) were measured in CRA fed and PBS fed mice 4 hours after final CRA challenge. Penh was recorded at the plateau of airways hyperresponsiveness, 50 mg/mL for 5 minutes for Penh and 25 mg/mL for 10 minutes for resistance. Minute ventilation (B), respiratory rate (C) and tidal volume (D) were measured in CRA fed and PBS fed mice 4 hours after final CRA challenge. Data were recorded for 5 minutes in response to 50 mg/mL of methacholine. Each value is the mean ± SEM for n = 18 (Figure 1A Penh, 1B, 1C, 1D) and n = 8 (Figure 1A Resistance). * = p < 0.05 comparing CRA fed to PBS fed mice.

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