Figure 4

GAD67 gene expression levels in large and small airway epithelium of healthy smokers compared to healthy nonsmokers. A. Average normalized gene expression levels of GAD67, assessed using HG-U133 Plus 2.0 microarray in large airway epithelium of 21 healthy nonsmokers and 31 healthy smokers. The ordinate shows the average normalized gene expression levels for GAD67. B. Average normalized gene expression levels of GAD67, assessed using HG-U133 Plus 2.0 microarray in small airway epithelium of 47 healthy nonsmokers and 58 healthy smokers. C. TaqMan confirmation of changes in GAD67 gene expression levels in large airways of 10 healthy nonsmokers and 12 healthy smokers. D. TaqMan confirmation of changes in GAD67 gene expression levels in small airways of 10 healthy nonsmokers and 12 healthy smokers. The ordinate shows average gene expression levels and error bars represent standard error.