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Table 1 Patients and clinical findings.

From: Decreased Toll-like receptor 8 expression and lower TNF-alpha synthesis in infants with acute RSV infection

Clinical findings

Controls (n = 10)

Bronchiolitis (n = 12)

Pneumonia (n = 3)

Total (n = 15)

Age (months)

5

(1-13)

2.5

(1-8.5)

1

(1-5)

2.5

(1-8.5)

Gestational age

40

(39-40)

40

(36-40)

38

(32-40)

40

(32-40)

Birth weight (kg)

3.4

(3.2-4.0)

3.4

(2.8-4.1)

3.1

(2.4-3.4)

3.4

(2.4-4.1)

Mode of delivery

(normal/caesarian surgery)

9/1

11/1

2/1

13/2

Apgar

10

(9-10)

10

(9-10)

10

(8-10)

10

(8-10)

WBC count (x109/L)

8.2

(4.3-14.7)

12.1

(4.6-18.7)

11

(9.4-13.2)

11.8

(4.6-18.7)

CRP (mg/L)

-

4.8

(1.2-8.9)

2.1

(1.4-11)

4.7

(1.2-11)

ESR (mm/h)

-

10

(5-30)

9

(5-25)

9

(5-30)

Wheezing (No. of cases)

-

12

3

15

Wheezing duration (days)

-

4.5

(1-6)

1

(1-3)

3

(1-6)

Hospital stay (days)

-

7.5

(4-10)

9

(7-10)

8

(4-10)

MOS (%)

-

91.5

(88-98)

90

(83-91)

91

(83-98)

MRR (/min)

-

55

(40-60)

50

(45-55)

55

(40-60)

Oxygen supplementation

(No. of cases)

-

6

2

8

Oxygen supplementation

(days)

-

1.5

(1-7)

7

(6-8)

4

(1-8)

Pulmonary X-ray scan

(No. of cases)

    

Negative

-

12

0

12

Infiltrate

-

0

3

3

  1. Infants with pneumonia (defined as crackles on auscultation and chest radiographs showing infiltrates) had also developed bronchiolitis (defined as wheezing with hypoxia and O2 saturation < 95%). Medians, range (in parentheses) and the number of patients (n) were determined. Minimal oxygen saturation (MOS) was measured by percutaneous oxymetry breathing ambient air.
  2. WBC - white blood cells, CRP - C-reactive protein, ESR - erythrocyte sedimentation rate, MRR - maximal respiratory rate (frequency) during hospitalization period