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Figure 8 | Respiratory Research

Figure 8

From: Decreased Toll-like receptor 8 expression and lower TNF-alpha synthesis in infants with acute RSV infection

Figure 8

Increased percentages of monocytes producing TNF-alpha in the convalescent phase. Fresh PBMC from RSV-infected infants (n = 10) in acute phase and convalescent phase 4-6 weeks after first sampling were stimulated with 5 μg/mL CL075 for 6 h in the presence of brefeldin A. Intracellular TNF-α was stained with anti-TNF-α APC-conjugated antibody in CD68-positive monocytes upon permeabilization. Non-parametric Kruskal-Wallis ANOVA test was acquired to confirm statistical significance and Mann-Whitney U-test was applied for intergroup analysis.

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