Figure 5
From: Early-life viral infection and allergen exposure interact to induce an asthmatic phenotype in mice
Development of AHR. (A) Airway responsiveness to increasing concentrations of β-methacholine, assessed by transpulmonary resistance (RL). (B) Transpulmonary resistance assessed as area under the curve. Significant differences compared to naïve animals shown as * = P < 0.05, ** = P < 0.01, *** = P < 0.001; compared to virus-infected, OVA-challenged animals (Virus/OVA) shown as ## = P < 0.01.