Figure 7
From: Cigarette smoke induces PTX3 expression in pulmonary veins of mice in an IL-1 dependent manner
Effect of cigarette smoke (CS) exposure and PTX3 deficiency on peribronchial lymphoid aggregates formation. A-D: Photomicrographs of lymphoid aggregates in CD3/B220 immunostained lung tissue of 24 weeks air and CS-exposed WT and Ptx3 KO mice (brown = CD3 positive cells and blue = B220 positive cells). E: Quantification of peribronchial lymphoid aggregates in lung tissue of WT and Ptx3 KO mice upon 24 weeks exposure to air or CS. Data are expressed as mean ± SEM (N = 8 animals/group; * p < 0.05).