Figure 7
Effects of JNK inhibitor SP600125 (10 μM) and dexamethasone (Dex, 1 μM) on nicotine-enhanced des-Arg9-bradykinin- (A, C) and bradykinin- (B, D) induced contractions. Tracheal segments were cultured for 4 days in presence of nicotine (Nic, 10 μM) together with vehicle or SP600125 (A, B) or dexamethasone (C, D). Each data point is derived from 10-12 experiments.