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Table 20 Summary results of the meta-analysis and publications bias

From: Asthma susceptible genes in Chinese population: A meta-analysis

      

Pubilication bias (Begg's test)

Gene

Polymorphism

Genotype investigated

Studies Number

Effect Model

OR(95%CI)

t

P

β2-AR

-46G/A

GG

13

Random

1.02(0.75, 1.38)

-0.66

0.525

 

-79G/C

GG

10

Fixed

0.86(0.58, 1.29)

1.60

0.148

IL-4R

-1902G/A

GG+GA

12

Random

1.30(0.94, 1.80)

0.92

0.377

 

-223G/A

GG

7

Random

0.92(0.63, 1.35)

-0.81

0.453

IL-4

-589C/T

CC+CT

8

Fixed

1.01(0.88, 1.16)

0.53

0.615

TNF-α

-308A/G

AA+AG

10

Random

1.42(1.09, 1.85)

1.38

0.205

FcεRIβ

-6843G/A

GG+GA

9

Random

1.49(1.01, 2.22)

2.82

0.026

 

-109C/T

CC

3

Fixed

0.96(0.62, 1.48)

-1.10

0.471

ACE

D/I

DD

6

Fixed

3.85(2.49, 5.94)

0.88

0.429

IL-13

-2044A/G

AA+AG

9

Random

1.49(1.07, 2.08)

1.93

0.095

 

-1923C/T

TT

5

Fixed

2.99(2.12, 4.24)

1.19

0.320

IL-1β

-511C/T

TT+TC

3

Fixed

1.10(0.76, 1.59_

-0.16

0.896

LT-α

+252A/G

GG+GA

6

Fixed

1.26(0.98, 1.62)

-0.02

0.985

TGF-β1

-509C/T

TT+TC

3

Fixed

1.17(0.83, 1.64)

8.57

0.074

CD14

-159C/T

TT+TC

6

Random

0.79(0.59, 1.06)

-0.41

0.700

ADAM33

T1-C/T

CC

3

Fixed

6.07(2.69, 13.73)

-8.22

0.077

RANTES

-28G/C

GG+GC

3

Fixed

1.64(1.09, 2.46)

0.87

0.544

 

-403A/G

AA+AG

3

Fixed

1.18(0.83, 1.67)

-0.37

0.777