Cytotoxic T cells expressing the co-stimulatory receptor NKG2 D are increased in cigarette smoking and COPD

Respiratory Research

Table 1 Demographics and spirometry values

	Never-smokers n = 21	Smokers n = 16	COPD Ex-smokers n = 19	COPD Smokers n = 16
Male:Female	11:10	7:9	13:6	4:12
Age	66 ± 5.2	61 ± 6.8	68 ± 5.8	64 ± 5.5
Smoking(pack years)	0 (0-0)	31 (21-42)	35 (18-42)	29 (24-48)
COPD stage^#	NA	NA	2 and 3	2 and 3
FEV₁/FVC %	78 (76-82)	79 (77-83)	55 (49-64)*	60 (57-63)*
FEV₁ % of predicted	101 (90-116)	110 (99-119)	46 (36-53)*	54 (39-68)*

Data are shown as mean±standard deviation for age, median and inter quartile range for all others. FEV₁: Forced expiratory volume in one second, measured post bronchodilatation; FVC: Forced vital capacity. # according to GOLD standard [3]. NA: not available. *indicate significant difference compared to smokers with normal lung function and never-smokers (p < 0.001).

ISSN: 1465-993X