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Figure 4 | Respiratory Research

Figure 4

From: Pharmacological characterisation of anti-inflammatory compounds in acute and chronic mouse models of cigarette smoke-induced inflammation

Figure 4

The effect of roflumilast on chronic CSE-induced inflammatory cell infiltrate. After 14 weeks of CSE, mice treated with roflumilast (p.o., q.d.) trended towards having reduced numbers of neutrophil (A), macrophage (B) and lymphocyte (C) in the BALF. Data from CSE mice are represented by black bars, data from sham controls represented by white bars, data from the CSE with compound treatment in gray, diagonal-striped bars. Data plotted as the mean ± sem with an n = 8-10 for each group. Significance (* = p < 0.05, ** = p < 0.01, *** = p < 0.001) was determined versus smoke vehicle control group.

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Respiratory Research

ISSN: 1465-993X

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