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Table 2 Characteristics of the control, COPD and IPF patients in the Hemoglobin alpha and beta Western blot analyses of the lung homogenates

From: Hemoglobin α and β are ubiquitous in the human lung, decline in idiopathic pulmonary fibrosis but not in COPD

 

Control

Smoker

COPD

Stage IV

IPF

Patients, n

7

7

7

7

Age, yr

65 ± 3

62 ± 3

58 ± 2

56 ± 3

Sex, M/F

4/3

6/1

4/3

5/2

Pack years, yr

7 ± 5 *

21 ± 6

31 ± 5**

6 ± 5 ***

FEV1 (%)

100 ± 6

88 ± 3

22 ± 5#

47 ± 6#

FVC (%)

102 ± 6

87 ± 4

47 ± 8#

43 ± 5#

  1. Data are presented as mean ± SEM.
  2. * Four of the controls were never smokers and two of the controls had smoked 10-15 years but stopped smoking at least 2 years before the study; one of the controls had smoked 30 years but stopped smoking one year before the study.
  3. ** All the patients were smokers, but had stopped smoking at least 2 years before the study. *** Five of the IPF patients were never smokers; two had smoked for over 5 years but stopped smoking at least two years before the study.
  4. # p < 0.05 versus control subjects and healthy smokers.
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Respiratory Research

ISSN: 1465-993X

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