| |
first visit day 1
|
second visit day 3/4
|
second visit day 3/4
| |
|---|
| |
all
|
Iota-Carrageenan
|
Placebo
|
p-value
|
|---|
|
FGF-2
|
5.9 (5.9)
|
2.5 (2.8)
|
7.5 (5.6)
|
0.04
|
|
Fractalkine
|
87.0 (74.5)
|
46.4 (32.4)
|
79.7 (39.3)
|
0.023
|
|
GRO
|
252 (233)
|
156 (112)
|
339 (417)
|
n.s.
|
|
G-CSF
|
45.5 (89.1)
|
10.9 (17.9)
|
78.5 (186)
|
n.s.
|
|
IL-8
|
18.7 (30.6)
|
14.4 (10.8)
|
21.0 (22.4)
|
n.s.
|
|
IL-1α
|
35.3 (30.0)
|
28.8 (14.4)
|
43.1 (28.9)
|
n.s.
|
|
IP-10
|
1790 (3177)
|
970 (1769)
|
3016 (4033)
|
n.s.
|
|
IL-10
|
1.6 (4.22)
|
0 (0)
|
5.5 (13.6)
|
0.049
|
|
IL-1ra
|
164 (129)
|
174 (320)
|
131 (85)
|
n.s.
|
|
IFN-α2
|
11.6 (8.0)
|
8.7 (4.1)
|
11.5 (5.6)
|
n.s.
|
|
IL-12(p40)
|
10.6 (14.0)
|
9.1 (9.7)
|
8.0 (9.8)
|
n.s.
|
- Comparison of cytokine levels on day 1 and day 3/4. Shown are mean levels in pg/ml ± standard deviation. Lower quantification limit was 3.2 pg/ml, values below were set to '0'. P-values: comparison verum versus placebo by Mann-Whitney U-test.
