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Figure 3 | Respiratory Research

Figure 3

From: Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFα and IL-13

Figure 3

Effect of IL-13 on oxytocin-evoked cytosolic free Ca 2+ concentration ([Ca 2+ ] i ). IL-13 (50 ng/ml) was pre-incubated for 24 hr before cells were exposed to 100 nM oxytocin. (A) Typical Ca2+ traces from cells incubated in the absence or presence of IL- 13. (B) Graphical representation of values for the Ca2+ peak phase from cells incubated in the absence or presence of IL-13. Results are expressed as the net increase in [Ca2+]i over basal (unstimulated) levels. Values are means ± SE of 3 separate experiments and are significantly different from oxytocin only control (P < 0.01). TNFα did not have a modulatory effect on oxytocin-induced calcium response in these cells.

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