Skip to main content

Advertisement

Table 1 Proportions of IL-13+ and IFN-γ+ T cells after culture.

From: Asthma and gender impact accumulation of T cell subtypes

Stimulus * Subset Subjects Median IQR n p
CD3+CD28 IL-13+ Control 0.8% 0.6 - 4.3 17 0.67
+IL-2   Asthma 1.8% 0.5 - 4.2 18  
  IFN-γ+ Control 2.9% 0.6 - 7.8 11 0.035
   Asthma 7.4% 5.1 - 20.2 19  
IL-2 IL-13+ Control 1.0% 0.7 - 3.2 24 0.0004
   Asthma 4.5% 2.5 - 5.3 18  
  IFN-γ+ Control 4.1% 2.4 - 10.3 19 0.0076
   Asthma 10.7% 7.2 - 24.2 19  
  1. * After 5-day (CD3+CD28+IL-2) or 6-day (IL-2) culture of PBL (anti-IL-12 monoclonal antibody included in all cultures), proportions of cytokine-producing T cells were determined by flow cytometry.
  2. Median and 25%-75% interquartile range (IQR) of the proportion of IL-13+ or IFN-γ+ T cell subsets.
  3. p-value for the significance of difference between control and asthmatic subjects (two-tailed Mann-Whitney test).