Figure 4

Effects of gender and asthma on T cell subset accumulation. Data obtained in the experiments for Figures 2 and 4 were reanalyzed, including both asthma and gender as independent variables in 2-way General Linear Model analyses of accumulation of IL-13⁺ and IFN-γ⁺ T cells. Each symbol indicates the number of: IL-13⁺ (left panels) and IFN-γ⁺ (right panels) T cells, expressed as a percent of the respective day 0 values for each subject after (A) 6-d culture with IL-2 + anti-IL-12 or (B) 5-d culture with CD3+CD28monoclonal antibody + IL-2 + anti-IL-12. Bars = geometric mean for each parameter. p-values from planned Tukey-Kramer multiple comparison tests are shown.