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Figure 8 | Respiratory Research

Figure 8

From: Differential effects of cytokines and corticosteroids on Toll-like receptor 2 expression and activity in human airway epithelia

Figure 8

TLR2-mediated ASL antimicrobial activity. Epithelia were pre-treated overnight with cytokines (TNF-α and IFN-γ), dexamethasone, or a combination of cytokines plus dexamethasone, then exposed to Pam3CSK4 (25 μg/ml) for 24 hours. Apical washings were obtained, and modified radial diffusion assays performed. Data represent fold change from control, TLR2-agonist exposed condition for the test organisms: Listeria monocytogenes (grey), Escherichia coli DH5α (white), and Pseudomonas aeruginosa PA01 (black). n = 3 donor samples. **P < 0.01.

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