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Figure 2 | Respiratory Research

Figure 2

From: PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells

Figure 2

Bradykinin-induced IL-8 release is increased by the PKA activator 6-Bnz-cAMP. hTERT-airway smooth muscle cells were stimulated with the indicated concentrations of 6-Bnz-cAMP in the absence (Basal) or presence of 10 μM bradykinin for 18 hrs. IL-8 release was assessed by ELISA. Results are expressed as mean ± SEM of separate experiments (n = 3-10). ***P < 0.001 compared to unstimulated control; # P < 0.05, ## P < 0.01 compared to bradykinin-stimulated control.

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