Table 2 Cytokine levels in plasma
CpG-ODN | ||||||
|---|---|---|---|---|---|---|
PBS | Control ODN | 6 | 24 | 48 | 168 (h) | |
IL-1β | 34.7 ± 6.3 | 28.8 ± 6.6 | 47.6 ± 14.9 | 56.6 ± 5.6*† | 42.4 ± 6.0*† | 25.0 ± 4.4 |
IL-10 | 39.0 ± 0.6 | 33.5 ± 4.1 | 35.6 ± 13.0 | 95.2 ± 17.0 | 122.3 ± 18.5*† | 46.1 ± 16.8 |
IFN-γ | 2.3 ± 1.0 | 10.6 ± 4.3 | 1.7 ± 0.6 | 12.5 ± 4.8 | 4.2 ± 1.8 | 8.3 ± 7.5 |
TNF-α | 759.0 ± 96.8 | 664.2 ± 78.0 | 550.3 ± 64.8 | 777.7 ± 83.0 | 690.8 ± 135.8 | 633.2 ± 74.0 |
IL-6 | 29.3 ± 18.8 | 14.1 ± 2.2 | 39.0 ± 7.0 | 124.3 ± 17.6*† | 46.2 ± 9.3 | 12.7 ± 6.2 |
IL-12p40 | 126.0 ± 4.8 | 116.4 ± 10.9 | 314.5 ± 65.8*† | 303.9 ± 20.9*† | 235.8 ± 30.2 | 120.2 ± 12.4 |
KC | 31.9 ± 4.9 | 32.0 ± 4.1 | 53.1 ± 13.4 | 92.7 ± 12.4*† | 47.8 ± 9.8 | 23.2 ± 3.7 |
MCP-1 | 16.0 ± 5.7 | 4.6 ± 3.9 | 48.2 ± 27.0 | 137.1 ± 41.5*† | 25.9 ± 9.5 | 13.6 ± 3.5 |
MIP-1α | 31.5 ± 4.4 | 29.2 ± 3.4 | 25.5 ± 7.6 | 65.0 ± 8.9 | 42.0 ± 7.2 | 21.3 ± 11.2 |
MIP-1β | 8.5 ± 2.5 | 6.3 ± 3.4 | 8.4 ± 3.4 | 23.6 ± 4.4† | 10.7 ± 2.8 | 2.7 ± 1.3 |