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Table 2 Cytokine levels in plasma

From: Intratracheal synthetic CpG oligodeoxynucleotide causes acute lung injury with systemic inflammatory response

    CpG-ODN
  PBS Control ODN 6 24 48 168 (h)
IL-1β 34.7 ± 6.3 28.8 ± 6.6 47.6 ± 14.9 56.6 ± 5.6*† 42.4 ± 6.0*† 25.0 ± 4.4
IL-10 39.0 ± 0.6 33.5 ± 4.1 35.6 ± 13.0 95.2 ± 17.0 122.3 ± 18.5*† 46.1 ± 16.8
IFN-γ 2.3 ± 1.0 10.6 ± 4.3 1.7 ± 0.6 12.5 ± 4.8 4.2 ± 1.8 8.3 ± 7.5
TNF-α 759.0 ± 96.8 664.2 ± 78.0 550.3 ± 64.8 777.7 ± 83.0 690.8 ± 135.8 633.2 ± 74.0
IL-6 29.3 ± 18.8 14.1 ± 2.2 39.0 ± 7.0 124.3 ± 17.6*† 46.2 ± 9.3 12.7 ± 6.2
IL-12p40 126.0 ± 4.8 116.4 ± 10.9 314.5 ± 65.8*† 303.9 ± 20.9*† 235.8 ± 30.2 120.2 ± 12.4
KC 31.9 ± 4.9 32.0 ± 4.1 53.1 ± 13.4 92.7 ± 12.4*† 47.8 ± 9.8 23.2 ± 3.7
MCP-1 16.0 ± 5.7 4.6 ± 3.9 48.2 ± 27.0 137.1 ± 41.5*† 25.9 ± 9.5 13.6 ± 3.5
MIP-1α 31.5 ± 4.4 29.2 ± 3.4 25.5 ± 7.6 65.0 ± 8.9 42.0 ± 7.2 21.3 ± 11.2
MIP-1β 8.5 ± 2.5 6.3 ± 3.4 8.4 ± 3.4 23.6 ± 4.4† 10.7 ± 2.8 2.7 ± 1.3
  1. All values (pg/mL) are expressed as the means ± SE (n = 5-6 in each group). *p < 0.05 was considered to be significantly different from the corresponding value of the PBS group. † p < 0.05 was considered to be significantly different from the corresponding value of the control ODN group.