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Table 1 Cytokine levels in bronchoalveolar lavage fluid

From: Intratracheal synthetic CpG oligodeoxynucleotide causes acute lung injury with systemic inflammatory response

    CpG-ODN
  PBS Control ODN 6 24 48 168 (h)
IL-1β 4.9 ± 2.1 3.4 ± 0.6 45.4 ± 3.0*† 56.7 ± 6.2*† 62.1 ± 8.0*† 12.0 ± 4.0
IL-10 3.0 ± 0.6 2.6 ± 0.4 5.1 ± 0.3 51.8 ± 12.2† 108.4 ± 23.1*† 2.6 ± 0.8
IFN-γ 2.8 ± 0.5 1.3 ± 0.3 2.0 ± 0.3 110.7 ± 38.1*† 39.9 ± 12.6 1.7 ± 0.3
TNF-α 41.2 ± 5.6 37.0 ± 1.9 75.1 ± 12.7 466.1 ± 184.1*† 153.8 ± 50.6 31.3 ± 2.5
IL-6 7.5 ± 1.7 3.5 ± 0.9 36.9 ± 8.8 150.0 ± 55.4*† 181.3 ± 69.0*† 3.2 ± 0.9
IL-12p40 15.3 ± 4.5 11.8 ± 1.6 396.9 ± 56.9*† 410.9 ± 57.8*† 453.1 ± 79.6*† 111.5 ± 45.8
KC 1.4 ± 0.3 2.0 ± 0.2 180.8 ± 38.5*† 75.0 ± 25.9 63.6 ± 16.4 2.4 ± 0.3
MCP-1 1.4 ± 0.4 1.6 ± 0.4 55.4 ± 20.7 965.9 ± 206.6*† 1295.7 ± 204.5*† 3.6 ± 2.5
MIP-1α 11.2 ± 1.4 3.6 ± 1.8 125.5 ± 50.7 321.6 ± 92.2*† 72.3 ± 15.6 4.1 ± 1.8
MIP-1β 1.6 ± 0.5 1.7 ± 0.3 17.6 ± 6.2 223.9 ± 16.0*† 158.9 ± 37.9*† 1.3 ± 0.3
  1. All values (pg/mL) are expressed as the means ± SE (n = 5-6 in each group). *p < 0.05 was considered to be significantly different from the corresponding value of the PBS group. †p < 0.05 was considered to be significantly different from the corresponding value of the control ODN group.