Figure 4

Representative histopathological findings of the lungs and the liver after CpG-ODN challenge. (A) CpG-ODN challenge caused numerous neutrophil accumulation in the alveolar space with thickening of the alveolar septa and areas of hemorrhage. (B) Intratracheal CpG-ODN induced marked liver damage, including disruption of normal architecture, necrosis, neutrophil infiltration, and hemorrhage. Original magnification × 100.