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Table 2 BAL Fluid Cell Characteristics

From: Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosis

 

IPF (n = 19)

Sar (n = 6)

CVD-IP (n = 8)

HV (n = 6)

Total cells

(105/ml)

6.2 ± 0.8

(1.9-14.8)

4.9 ± 0.3

(4.0-6.0)

11.2 ± 3.1*#£

(1.1-27.9)

2.7 ± 0.5

(0.6-4.0)

Macrophage

(%)

78.0 ± 2.6∫

(60.2-97.0)

62.9 ± 10.8* (29.5-95.0)

44.0 ± 9.9"§ (5.5-74.5)

95.6 ± 0.3§$

(94.7-96.6)

Lymphocyte

(%)

11.3 ± 2.1

(0-27.4)

34.6 ± 10.5*‡

(5.0-68.5)

33.8 ± 8.7*‡

(12.0-87.5)

3.1 ± 0.2

(2.6-4.0)

Neutrophil

(%)

6.1 ± 1.4

(1.0-23.0)

1.7 ± 0.8

(0-4.0)

18.4 ± 8.6|#£

(0-65.5)

1.1 ± 0.1

(0.7-1.6)

Eosinophil

(%)

4.4 ± 1.1∫#

(0-14.5)

0.5 ± 0.3

(0-1.9)

1.7 ± 0.9

(0-7.5)

0.2 ± 0.2

(0-0.9)

CD4/CD8

3.1 ± 0.6

(0.2-9.6)

11.2 ± 4.0&¥

(2.4-29.3)

1.8 ± 0.5

(0.4-3.9)

N.D.

  1. IPF, idiopathic pulmonary fibrosis; Sar, sarcoidosis; CVD-IP, collagen vascular disease with interstitial pneumonia; HV, healthy volunteers; N.D., not determined
  2. All data were shown as mean ± SEM.
  3. "p < 0.0001 v.s. HV, *p < 0.005 v.s. HV, ∫p < 0.05 v.s. HV
  4. †p < 0.0005 v.s. CVD-IP, &p < 0.005 v.s. CVD-IP
  5. $p < 0.005 v.s. Sar, #p < 0.05 v.s. Sar
  6. §p < 0.0001 v.s. IPF, ¥p < 0.001 v.s. IPF, ‡p < 0.005 v.s. IPF, £p < 0.05 v.s. IPF