Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosis

Table 1 Patient Characteristics and Lung Functions

	IPF	Sar	CVD-IP	HV
Male/female	18/1	3/3	3/6	6/0
Age (range)	67.0 ± 1.9 (48-83)	58.5 ± 23.2 (24-76)	59.4 ± 14.8 (33-76)	N.D. (20-24)
Smoker	16*^†	6*	3	0
PaO₂/FIO₂	372 ± 9.2 (307-453)	419 ± 29 (319-529)	358 ± 23 (278-448)	N.D.
%VC	62 ± 4.6 (33-110)	101 ± 6.1^# (83-120)	67 ± 6.6 (43-98)	N.D.
DLCO/VA	4.0 ± 0.2^† (2.6-5.4)	4.8 ± 0.4 (4.1-6.3)	7.1 ± 1.9 (4.4-14.0)	N.D.

IPF, idiopathic pulmonary fibrosis; Sar, sarcoidosis; CVD-IP, collagen vascular disease with interstitial pneumonia; HV, healthy volunteers; N.D, not determined; DLco, single-breath carbon monoxide diffusing capacity; VA, alveolar ventilation per minute
Age data and lung function parameters are shown as mean ± SEM.
*p < 0.001 v. s. HV
^§p < 0.001 v. s. CVD-IP, ^†p < 0.005 v. s. CVD-IP
^#p < 0.0005 vs. IPF

ISSN: 1465-993X