Effects of intratracheal administration of nuclear factor-kappaB decoy oligodeoxynucleotides on long-term cigarette smoke-induced lung inflammation and pathology in mice

Table 5 Lung Morphologic analysis of mice on 92 days of persistent smoke exposure.

Treatment	Lm(μm)	Am(μm²)	DI
NS	46.05 ± 6.71	1019.71 ± 95.62	42.89 ± 9.19
Decoy	45.07 ± 8.23	1137.15 ± 246.28	48.73 ± 15.87
Scr	41.48 ± 4.51	1231.02 ± 139.88	44.54 ± 11.70
Pr > Chi-Square	0.4573	0.0643	0.4712

Data were analyzed by Nonparametric Mann-Whitney U-test and expressed as mean ± STD. Lm: linear intercept; Am: mean alveolar surface; DI: destructive index; NS: normal saline-treated smoke-exposed mice; Decoy: decoy NF-κB ODNs-treated smoke-exposed mice; Scr: scrambled ODNs-treated smoke-exposed mice. n = 8

ISSN: 1465-993X