Figure 4

Tie 1 mRNA expression during hormonal treatment. mRNA content expressed as percentage of control normalized to GAPDH. Data are shown as mean ± SEM (n = 4-9 group). DEX treatment significantly decreased Tie1 expression at both 10 and 15 days (*p = 0.0006 and **p = 0.0022 respectively) as compared to same days controls. RA treatment alone did not change Tie 1 expression and also failed to restore DEX-induced decrease in Tie 1 expression (* and **p = 0.04).