From: Effects of cigarette smoke on endothelial function of pulmonary arteries in the guinea pig
3 months | 6 months | ||||
---|---|---|---|---|---|
Control (n = 8) | CS-Exposed (n = 5) | Control (n = 8) | CS-Exposed (n = 13) | ||
Pulmonary artery | Diameter (mm) | 2.26 (2.10–2.49) | 2.37 (2.11–2.45) | 2.26 (2.13–2.39) | 2.19 (2.15–2.40) |
Wall area (mm 2 ) | 0.26 (0.24–0.33) | 0.38 (0.30–0.42) | 0.27 (0.24–0.31) | 0.35* (0.32–0.41) | |
Wall thickness (μm) | 38 (36–43) | 50 (43–57) | 35 (33–40) | 51‡ (45–53) | |
Aorta | Diameter (mm) | 2.21 (2.14–2.30) | 2.34 (2.17–3.80) | 2.22 (2.07–2.32) | 2.28 (2.24–2.36) |
Wall area (mm 2 ) | 0.58 (0.51–0.65) | 0.77 (0.59–0.92) | 0.50 (0.46–0.65) | 0.63 (0.57–0.74) | |
Wall thickness (μm) | 82 (74–92) | 96 (86–117) | 77 (70–87) | 88 (80–97) |