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Table 5 Sensitivity ratios for the different lung regions (analysis of covariance model)a

From: Exploring the optimum approach to the use of CT densitometry in a randomised placebo-controlled study of augmentation therapy in alpha 1-antitrypsin deficiency

 

PD15 (g/L)

Outcome measure

LS mean change from baseline

Standard error

Sensitivity indexb

F-testc

F-testd

Whole lung

-4.12

0.539

7.64

-

-

Basal region

-3.84

0.604

6.36

NS

-

Middle region

-3.82

0.673

5.68

NS

0.642

Apical region

-3.80

1.001

3.80

< 0.05

< 0.05

  1. PD15, 15th percentile lung density; LS mean, least squares mean; NS, not significant.aResults based on estimates for placebo group only. bRatio of absolute value of mean change divided by standard error. cRatio of outcome measure as compared to PD15 (whole lung). dRatio of outcome measure as compared to PD15 (basal region).
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Respiratory Research

ISSN: 1465-993X

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