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Table 4 Change in flow-volume spirometry variables in subjects with and without airflow limitation at the baseline in the population sample

From: Responses of FEV6, FVC, and FET to inhaled bronchodilator in the adult general population

 

FEV1/FVC ≥ LLN*

(n = 537)

mean (SD)

FEV1/FVC < LLN*

(n = 91)

mean (SD)

p value

change of FEV1 (ml)

66.2 (99.9)

142.6 (139.1)

p < 0.001

(% from baseline)

1.9 (2.9)

6.2 (6.4)

p < 0.001

change of FEV6 (ml)

-27.3 (98.0)

68.8 (160.1)

p < 0.001

(% from baseline)

-0.7 (2.5)

2.4 (5.4)

p < 0.001

change of FVC (ml)

-52.8 (103.2)

15.4 (192.3)

p < 0.001

(% from baseline)

-1.3 (2.6)

0.8 (5.6)

p < 0.001

change of FET (s)

-0.2 (2.5)

-0.4 (3.5)

p = 0.563

(% from baseline)

0.8 (24.1)

-1.6 (22.3)

p = 0.370

  1. FET = forced expiratory time; FEV1 = forced expiratory volume in one second; FEV6 = forced expiratory volume in six seconds; FVC = forced vital capacity; LLN = lower limit of normal
  2. * predicted values from [24]