Figure 2

Individual changes of forced vital capacity (FVC) and forced expiratory volume in six seconds (FEV ₆ ) after bronchodilation in the general adult population (n = 628). The dotted lines represent the significant change limit of 12% from the baseline [14] for FVC. All subjects with a change over 12% also fulfilled the absolute change criterion of 200 ml. The thick arrow highlights one subject with prolonged post-bronchodilation FET resulting in increase of FVC in the absence of significant change in FEV₆. The small arrows show subjects with significantly improved FEV₆ in the absence of increase in FVC, caused by shorter exhalations in post-bronchodilation spirometry. ICC = intra-class correlation.