Figure 4

Protein levels of cytokines and chemokines in the lung homogenates. The 4 groups of mice were intratracheally inoculated with vehicle, CSBG, OVA, or CSBG + OVA for 4 wk. Lungs were removed and frozen 24 h after the last intratracheal administration. Protein levels of interleukin (IL)-4, IL-5, IL-13, IL-17A, granulocyte/macrophage-colony-stimulating factor (GM-CSF), eotaxin, macrophage inflammatory protein (MIP)-1α (C), and keratinocyte-derived chemoattractant (KC) in the lung homogenate supernatants were analyzed using ELISA. The results are presented as the mean ± SE (n = 8 in each group). * P < 0.05 and ** P < 0.01 vs. vehicle; ^# P < 0.05 and ^## P < 0.01 vs. OVA; ^$ P < 0.05 and ^$$ P < 0.01 vs. CSBG.