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Table 4 Family-based association analysis of IPO13 polymorphisms on methacholine hyperresponsiveness (PC20) in childhood asthma.

From: Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma

  Nedocromil/Placebo Budesonide
Marker Number of informative Families P-value Number of informative families P-value
rs6671164 48 0.042 16 0.504
rs4448553 46 0.005 18 0.694
rs1990150 21 0.094 7 0.225
rs2240447 46 0.008 18 0.498
rs2486014 10 0.144 2 0.419
rs2301993 47 0.004 16 0.532
rs2301992 5 0.313 2 0.621
rs1636879 10 0.329 3 0.322
rs7412307 38 0.108 14 0.865
rs2428953 13 0.708 5 0.221
  1. Treatment-stratified analysis of repeated measures of methacholine PC20 performed using FBAT-PC as implemented in PBAT.