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Table 1 Inflammatory mediator levels in sputum from CF and COPD subjects.

From: Macrorheology of cystic fibrosis, chronic obstructive pulmonary disease & normal sputum

 

Cystic fibrosis

 

NE (mu/μl)

IL-8 (X102 ng/mL)

TCC (ng/mL)

MPO (mg/L)

Mucoid (n = 1)

2.75

0.85

0

34.30

Mucopurulent (n = 6)

13.85 (8.31–42.89)

1.22 (0.89–3.94)

0 (0–0.73)

53.47 (39.13–213.35)

Purulent (n = 6)

31.95 (14.94–62.13)

2.11 (0.91–34.35)

30.36 (0–326.44)

139.41 (51.44–238.15)

P value *

0.049

0.141

0.089

0.169

 

COPD

Mucoid (n = 4)

0 (0–1.33)

6.52 (3.51–8.14)

  

Mucopurulent (n = 2)

4.5 (0–9)

9.77 (5.93–13.6)

  

Purulent (n = 1)

35.11

6.15

  

P value *

0.20

0.85

  
  1. (Values presented are median (range). NE – neutrophil elastase activity, IL-8 – interleukin-8, TCC – terminal complement complex, MPO – myeloperoxidase. * by Kruskal-Wallis Test).
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Respiratory Research

ISSN: 1465-993X

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