Figure 5From: Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro Effect of poly-L-arginine on basal, LPS- and TNF-α-induced IL-6 (B, D) and IL-8 (A, C) production by NHBE cells. Cells were exposed for 20 h to normal medium with or without 5 μg/ml poly-L-arginine and a concentration range of LPS or TNF-α. One out of two experiments is shown (triplicate samples; mean ± SEM). Poly-L-arginine significantly enhanced TNF-α-induced IL-6 and IL-8 production (P < 0.0001 and P < 0.0001, respectively).Back to article page