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Table 2 Inflammatory lesion scores in OVA immunized group and control group

From: Does unrestrained single-chamber plethysmography provide a valid assessment of airway responsiveness in allergic BALB/c mice?

Different group Perivascular eosinophilia Peribronchiolar eosinophilia Edema Epithelial damage
OVA-1D-I 3(1–3) 1(1–2) 1(1–2) 1(1–3)
OVA-1D-N 3(2–3) 1(1–2) 1(1–2) 1(1–3)
OVA-3D-I 4(3–5) 2.5(2–3) 1(1–2) 2(1–3)
OVA-3D-N 3.5(3–5) 2(2–3) 1(1–2) 2(1–3)
Control(I) 0(0–0)* 0(0–0)* 0(0–0)* 0(0–1)*
  1. All mice were sensitized with OVA (10 ug, i.p) on days 0, 7 and 14. Mice in OVA-1D group were single-dose challenged on day 28. On day 29, responsiveness of mice was carried out with invasive measurements (OVA-1D-I group) or non-invasive measurements (OVA-1D-N group). Mice in OVA-3D group were three-dose challenged on day 28, 29, 30. On day 31, responsiveness of mice was carried out by invasive (OVA-3D-I group) or Penh measurements (OVA-3D-N group). The mice in Control (I) group were sensitized and challenged with normal saline.
  2. * P < 0.05 for Control group versus OVA immunized group, Kruskal-Wallis test.
  3. P < 0.01 for OVA-3D group versus OVA-1D group, Kruskal-Wallis test.