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Table 2 Body weight, heart weight, and hemodynamic data after exposure to 10% O2 (hypoxia) or room air

From: Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice

 

Normoxia

 

Hypoxia

 
 

IL-6+/+ n = 8

IL-6-/- n = 8

IL-6+/+ n = 8

IL-6-/- n = 8

Final body weight (g)

25.2 ± 0.3

22.9 ± 0.5**

24.7 ± 0.6

20.6 ± 0.7**

RV/BW (mg/g)

0.96 ± 0.02

0.85 ± 0.03

1.24 ± 0.07$$$

1.02 ± 0.07*

LV/BW (mg/g)

3.8 ± 0.06

3.7 ± 0.15

3.6 ± 0.1

3.9 ± 0.1

Heart rate (beats/min)

308 ± 21

318 ± 24

327 ± 11

318 ± 23

  1. All values are mean ± SEM.
  2. *P < 0.05 and **P < 0.01 compared with corresponding values in wild type mice.
  3. $ P < 0.05 and $$ P < 0.01 compared with corresponding values under normoxia.
  4. RV/BW, right ventricular weight/body weight; LV/BW, left ventricular weight/body weight.
(normoxia)