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Figure 5 | Respiratory Research

Figure 5

From: Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation

Figure 5

Lung IR-induced alveolar MPO content is attenuated by A2AAR activation. MPO content in BAL fluid was significantly induced in lungs from WT and A2AAR KO mice after IR (*p < 0.01 vs. WT Sham). MPO content was significantly attenuated by ATL313 treatment in WT mice but not in A2AAR KO mice (#p < 0.001, WT IR+ATL313 vs. WT IR). WT Sham, WT lungs undergoing perfusion only; WT IR, WT lungs undergoing IR; KO IR, A2AAR KO lungs undergoing IR; KO IR+ATL313, A2AAR KO IR lungs treated with ATL313 (30 nM) during reperfusion.

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